4-Aminobutyrate aminotransferase

4-aminobutyrate aminotransferase (or GABA transaminase) is an enzyme which catalyzes the conversion of 4-aminobutanoic acid (GABA) and 2-oxoglutarate into succinic semialdehyde and glutamate.

Inhibitors

Transferase: nitrogenous groups (EC 2.6)

2.6.1: Transaminases	Aspartate transaminase (GOT1, GOT2) · Alanine transaminase · GABA transaminase · Tyrosine aminotransferase · Ornithine aminotransferase · Branched chain aminotransferase · Alanine-glyoxylate transaminase (AGXT)

2.6.3: Oximinotransferases	Oximinotransferase

2.6.99: Other	Pyridoxine 5'-phosphate synthase

B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6

histidine→histamine	anabolism: Histidine decarboxylase catabolism: Histamine N-methyltransferase · Amine oxidase

tyrosine→dopamine→epinephrine	anabolism: Tyrosine hydroxylase · Aromatic L-amino acid decarboxylase · Dopamine beta hydroxylase · Phenylethanolamine N-methyltransferase catabolism: Catechol-O-methyl transferase · Monoamine oxidase

glutamate→GABA	anabolism: Glutamate decarboxylase catabolism: 4-aminobutyrate aminotransferase · 4-aminobutyrate transaminase

tryptophan→serotonin→melatonin	Tryptophan hydroxylase · Aromatic L-amino acid decarboxylase · Acetylserotonin O-methyltransferase

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)